IGCSE Practice

Cambridge IGCSE·Co-ordinated Sciences 0654·Biology Diseases Immunity
📋Key knowledge — Diseases Immunity

Key facts & rules

  • Pathogen types: bacteria (e.g. tuberculosis, Salmonella), viruses (e.g. influenza, HIV), fungi, protists (e.g. malaria).
  • Transmission: direct contact, droplets, contaminated food/water, vectors (e.g. mosquitoes).
  • Physical defences: skin, mucus, cilia (in trachea), stomach acid.
  • Phagocytes: engulf and destroy pathogens (non-specific).
  • Lymphocytes: produce specific antibodies that bind to antigens on pathogens.
  • Memory cells: remain after infection → faster response if same pathogen returns (immunity).
  • Vaccination: introduces antigens (dead/weakened/antigen only) → immune system produces antibodies + memory cells.
  • Antibiotics: kill bacteria — NOT effective against viruses. Overuse causes antibiotic resistance.

IGCSE Biology — Diseases & immunity

112 Cambridge IGCSE 0654 biology past paper questions on diseases & immunity, organised by subtopic. Pick a subtopic to start practising.

About diseases & immunity on IGCSE 0654

Pathogens and transmissible disease, the body's defences, the immune response, and vaccination.

Diseases & immunity subtopics

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