IGCSE Practice

Cambridge IGCSE·Co-ordinated Sciences 0654·Biology Heart Circulatory System
📋Key knowledge — Transport In Animals

Formulas & equations

  • Cardiac output = heart rate × stroke volume

Key facts & rules

  • Double circulation: pulmonary (heart → lungs → heart) and systemic (heart → body → heart).
  • Arteries: carry blood AWAY from heart; thick walls, small lumen, high pressure, no valves.
  • Veins: carry blood TOWARDS heart; thin walls, large lumen, low pressure, have valves.
  • Capillaries: one cell thick wall, where exchange of gases and nutrients occurs.
  • Red blood cells: no nucleus, biconcave, contain haemoglobin — carry O₂.
  • Haemoglobin + O₂ ⇌ oxyhaemoglobin (in lungs); releases O₂ in tissues.
  • White blood cells: phagocytes (engulf pathogens) and lymphocytes (produce antibodies).
  • Plasma: transports dissolved substances — glucose, CO₂, urea, hormones, antibodies.
  • Platelets: involved in blood clotting.
  • Heart: left side pumps oxygenated blood; right side pumps deoxygenated blood.

IGCSE Biology — Heart & circulatory system

15 Cambridge IGCSE 0654 questions on heart & circulatory system, across all three components.

About heart & circulatory system on IGCSE 0654

Every Cambridge IGCSE Co-ordinated Sciences 0654 question on heart & circulatory system (Transport in animals, Biology), across all three exam components. Theory and alternative-to-practical come with full mark schemes; multiple choice is interactive — click an option to check it.

Theory

Papers 3 & 4 · 4 questions · Structured written questions, each with its full mark scheme.
Heart & circulatory system — Extended theory questions4 total · Paper 4

Exercise 1 — IGCSE 0654 Jun 2025 Paper 43 Q2

Cambridge past paperExtended9 marks Paper 43Jun 2025
IGCSE 0654 Jun 2025 Paper 43 Question 2 — Heart & circulatory system
Show mark scheme
Mark scheme for IGCSE 0654 Jun 2025 Paper 43 Q2

Exercise 2 — IGCSE 0654 Jun 2023 Paper 43 Q1

Cambridge past paperExtended12 marks Paper 43Jun 2023
IGCSE 0654 Jun 2023 Paper 43 Question 1 — Heart & circulatory system
Show mark scheme
Mark scheme for IGCSE 0654 Jun 2023 Paper 43 Q1

Exercise 3 — IGCSE 0654 Nov 2023 Paper 43 Q1

Cambridge past paperExtended9 marks Paper 43Nov 2023
IGCSE 0654 Nov 2023 Paper 43 Question 1 — Heart & circulatory system
Show mark scheme
Mark scheme for IGCSE 0654 Nov 2023 Paper 43 Q1
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Multiple choice

Papers 1 & 2 · 11 questions · Click an option (A–D) to check your answer instantly.
Heart & circulatory system — Core multiple choice questions5 total · Paper 1

Exercise 1 — IGCSE 0654 Oct/Nov 2025 Paper 12 Q7

Cambridge past paperCore1 mark Paper 12Oct/Nov 2025
IGCSE 0654 Oct/Nov 2025 Paper 12 Question 7 — Heart & circulatory system
Show answer
Correct answer: A

Exercise 2 — IGCSE 0654 May/June 2025 Paper 12 Q8

Cambridge past paperCore1 mark Paper 12May/June 2025
IGCSE 0654 May/June 2025 Paper 12 Question 8 — Heart & circulatory system
Show answer
Correct answer: D

Exercise 3 — IGCSE 0654 March 2025 Paper 12 Q10

Cambridge past paperCore1 mark Paper 12March 2025
IGCSE 0654 March 2025 Paper 12 Question 10 — Heart & circulatory system
Show answer
Correct answer: B

Exercise 4 — IGCSE 0654 Oct/Nov 2025 Paper 13 Q7

Cambridge past paperCore1 mark Paper 13Oct/Nov 2025
IGCSE 0654 Oct/Nov 2025 Paper 13 Question 7 — Heart & circulatory system
Show answer
Correct answer: A
Heart & circulatory system — Extended multiple choice questions6 total · Paper 2

Exercise 5 — IGCSE 0654 Oct/Nov 2025 Paper 21 Q8

Cambridge past paperExtended1 mark Paper 21Oct/Nov 2025
IGCSE 0654 Oct/Nov 2025 Paper 21 Question 8 — Heart & circulatory system
Show answer
Correct answer: C

Exercise 6 — IGCSE 0654 Oct/Nov 2025 Paper 22 Q7

Cambridge past paperExtended1 mark Paper 22Oct/Nov 2025
IGCSE 0654 Oct/Nov 2025 Paper 22 Question 7 — Heart & circulatory system
Show answer
Correct answer: B

Exercise 7 — IGCSE 0654 May/June 2025 Paper 23 Q6

Cambridge past paperExtended1 mark Paper 23May/June 2025
IGCSE 0654 May/June 2025 Paper 23 Question 6 — Heart & circulatory system
Show answer
Correct answer: C

Exercise 8 — IGCSE 0654 Oct/Nov 2025 Paper 23 Q7

Cambridge past paperExtended1 mark Paper 23Oct/Nov 2025
IGCSE 0654 Oct/Nov 2025 Paper 23 Question 7 — Heart & circulatory system
Show answer
Correct answer: D
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